Inventor · Seattle, WA, US

John E. Sims

67Patents
16h-index
31Co-inventors
84Inventor score

Filing activity: Feb 25, 1988 → Sep 16, 2014

Most-cited inventions

PatentTitleAreaCited byStatus
US4968607A Interleukin-1 receptors Chemistry; Metallurgy 158 Expired
US5180812A Soluble human interleukin-1 receptors, compositions and method of use Emerging Cross-Sectional Technologies 98 Expired
US5081228A Interleukin-1 receptors Emerging Cross-Sectional Technologies 72 Expired
US5488032A Method of using soluble human interleukin-1 receptors to suppress inflammation Emerging Cross-Sectional Technologies 65 Expired
US7261894B2 Methods of treating inflammatory and/or autoimmune disease Human Necessities 57 Expired
US5767064A Soluble type II interleukin-1 receptors and methods Human Necessities 40 Expired
US5319071A Soluble interleukin-1 receptors Emerging Cross-Sectional Technologies 36 Expired
US5492888A Method of using soluble human interleukin-1 receptors to suppress immune responses Emerging Cross-Sectional Technologies 32 Expired
US5464937A Type II Interleukin-1 receptors Human Necessities 32 Expired
US5350683A DNA encoding type II interleukin-1 receptors Human Necessities 26 Expired
US6555520B2 Human TSLP DNA and polypeptides Human Necessities 24 Expired
US5776731A DNA encoding type-I interleukin-I receptor-like protein designated 2F1 Human Necessities 23 Expired
US5296592A Process for purifying interleukin-1 receptors Chemistry; Metallurgy 20 Expired
US7304144B2 Antibodies binding to human TSLP Polypeptides Human Necessities 18 Expired
US5576191A Cytokine that binds ST2 Emerging Cross-Sectional Technologies 18 Expired
US5422248A DNA sequences encoding granulocyte-colony stimulating factor receptors Chemistry; Metallurgy 16 Expired
US5589456A Granulocyte-colony stimulating factor receptors Chemistry; Metallurgy 14 Expired
US6511665B1 Antibodies to interleukin-1 receptors Chemistry; Metallurgy 13 Expired
US8034771B2 IL-1F6 polypeptides Physics 12 Active
US8481021B2 IL-1F5 polypeptides Physics 11 Active
US6589764B1 IL-18 receptor fusion proteins Chemistry; Metallurgy 9 Expired
US7033783B2 Polynucleotide encoding IL-1 zeta polypeptide Physics 8 Expired
US7405058B2 Human TSLP polynucleotides Human Necessities 8 Active
US8871192B2 IL-1F8 polypeptides Physics 7 Active
US6692740B2 ACPL antibodies Chemistry; Metallurgy 7 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.