Patent · US Active

Kinase inhibitors

US10000482B2 · kind B2 · utility

1Cited by

1References

21Claims

0Family size

Assignee

Origenis GMBH · DE

Inventors

Michael Almstetter · Martinsried, DE
Michael Thormann · Martinsried, DE
Andreas Treml · Martinsried, DE
Roland Koestler · Martinsried, DE
Nasser Yehia · Martinsried, DE

Key dates

Filing date	Oct 18, 2013
Grant date	Jun 19, 2018
Priority date	—
Expiry date	Oct 18, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.