Stabilisation of radiopharmaceutical precursors
US10000518B2 · kind B2 · utility
0Cited by
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5Claims
0Family size
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Key dates
| Filing date | Nov 18, 2005 |
| Grant date | Jun 19, 2018 |
| Priority date | — |
| Expiry date | Oct 12, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-ß-D-mannopyranose which are used as precursors for production of radiofluoridated sugar derivatives for use in in vivo imaging procedures such as positron emission tomography (PET). The method comprises storing the non fluoridated sugar derivative in an organic solvent. The resultant formulations of the non fluoridated sugar derivative and cassettes for automated synthesis apparatus comprising the same are also claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.