CD147 as receptor for pilus-mediated adhesion of Meningococci to vascular endothelia
US10000545B2 · kind B2 · utility
0Cited by
43References
5Claims
0Family size
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Key dates
| Filing date | Jul 15, 2013 |
| Grant date | Jun 19, 2018 |
| Priority date | — |
| Expiry date | Jul 15, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns the use of an inhibitor of an interaction between type IV pilus-associated protein and CD147 for preventing or treating meningoccal bacteraemia and/or infection. The present invention also relates to the combined use of such inhibitor and of an anti-bacterial compound, such as one used to prevent or treat a meningococcal infection. The invention also relates to a method for the prevention and/or treatment of meningococcal bacteraemia and/or infection, and to a method for screening inhibitors of the interaction between type IV pilus-associated protein and CD147.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.