Monoclonal antibody and a method thereof

US10000573B2 · kind B2 · utility

Assignees

• Centro de Inmunología Molecular · CU
• Biocon Ltd. · IN

Inventors

• Ramakrishnan Melarkode · Savanuru, IN
• Pradip Nair · Savanuru, IN
• Sundaraj David Rajkumar · Poonamallee, IN
• Kedarnath Sastry · Savanuru, IN
• Monalisa Chatterji · Bengaluru, IN
• Laxmi Adhikary · Savanuru, IN
• Hema Balasubramanian · Bengaluru, IN
• Jose Enrique Montero Casimiro · Boyeros, CU
• Josefa Lombardero Valladares · Boyeros, CU
• Rolando Perez Rodriguez · Havana, CU

Key dates

• Filing date: May 31, 2017
• Grant date: Jun 19, 2018
• Expiry date: May 31, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/76
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a humanized IgG1 isotype anti-CD6 antibody (T1h) that binds to the Scavenger receptor cysteine-rich (SRCR) domain 1 (D1) of CD6 present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cells types.