Patent · US Active

Compositions comprising polypeptides

US10000574B2 · kind B2 · utility

2Cited by

2References

15Claims

0Family size

Assignee

AMGEN RESEARCH (MUNICH) GMBH · DE

Inventors

Robert Hofmeister · Scituate, US
Nadja Prang · Roma, IT
Andreas Wolf · Gauting, DE
Frank Hanakam · Birkenfeld, DE
Thomas Urbig · Birkenfeld, DE
Christian Itin · Menlo Park, US
Patrick Baeuerle · Gauting, DE

Key dates

Filing date	Nov 26, 2004
Grant date	Jun 19, 2018
Priority date	—
Expiry date	Apr 6, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/56
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to compositions comprising polypeptides, especially polypeptides capable of specifically binding predetermined antigens. The polypeptide in the composition comprises at least two antigen binding sites. These at least two antigen binding sites are located on a single polypeptide chain. One of the at least two antigen binding sites specifically binds the human CD3 antigen. The polypeptide may exist in both monomeric form and multimeric form. The multimeric form of the polypeptide constitutes no more than 5% of the total weight of the combined monomeric and multimeric forms of said polypeptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.