3D determination of cell chirality
US10001472B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jun 24, 2016 |
| Grant date | Jun 19, 2018 |
| Priority date | — |
| Expiry date | Jun 24, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5005
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein is a method for determining chirality of a cell. The method includes culturing a cell on a base layer having a cell growth material. The method includes forming a top layer on the base layer after the cell has attached to the base layer, the top layer having a cell growth material. The base layer and the top layer form a graded 3D substrate. The intrinsic bias of the cell is determined from the directionality of spontaneous cell rotation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.