Therapeutic compositions and methods for antibody and Fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells
US10005820B2 · kind B2 · utility
7Cited by
39References
24Claims
0Family size
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Key dates
| Filing date | Feb 15, 2012 |
| Grant date | Jun 26, 2018 |
| Priority date | — |
| Expiry date | Feb 15, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/74
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present application relates to the use of bacterial minicells as targeted delivery agents in vivo and in vitro. Described herein are genetically engineered eubacterial minicells designed to preferentially target and deliver therapeutically relevant agents using a minicell surface coupling molecule capable of binding and displaying antibodies or other Fc-containing targeting moiety fusions and conjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.