Compositions and methods related to diseases associated with deposits of amyloid, tau, and alpha-synuclein
US10005825B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Feb 20, 2015 |
| Grant date | Jun 26, 2018 |
| Priority date | — |
| Expiry date | Feb 20, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions, comprising one or more immunogens, wherein each immunogen comprises at least two regions, wherein one region comprises at least one amyloid-β (Aβ) B cell epitope or at least one Tau B cell epitope or at least one α-synuclein B cell epitope or combinations thereof, and a second region comprises at least one foreign T helper cell (Th) epitope, and usually multiple foreign Th epitopes. Methods of making and using the compositions are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.