Raman spectroscopy for detection of glycated analytes
US10006922B2 · kind B2 · utility
2Cited by
18References
39Claims
0Family size
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Key dates
| Filing date | Dec 21, 2012 |
| Grant date | Jun 26, 2018 |
| Priority date | — |
| Expiry date | Dec 21, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the optical measurement of blood analytes, such as glycated hemoglobin (HbA1c) and serum albumin as a functional metric of mean blood glucose in the diagnosis of diabetic patients. Non-enhanced Raman spectroscopy is employed as the analytical method for quantitative detection of blood analytes. Using processing techniques, non-enzymatic glycosylation (glycation) of the analytes results in measurable and highly reproducible changes in the acquired spectral data, which enable the accurate measurements and classification of glycated and unglycated analytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.