Crystalline forms of vilazodone hydrochloride and vilazodone free base

US10011590B2 · kind B2 · utility

Assignee

• DR. REDDY'S LABORATORIES LIMITED · IN

Inventors

• Javed Iqbal · Hyderabad, IN
• Srinivas ORUGANTI · Hyderabad, IN
• Rajesh Kumar Rapolu · Hyderabad, IN
• Vishweshwar PEDDY · Hyderabad, IN
• Rajesham Boge · Hyderabad, IN
• Deepika PATHIVADA · Hyderabad, IN
• Dharma Jagannadha Rao VELAGA · Visakhapatnam, IN
• Sesha Reddy Yarraguntla · Hyderabad, IN
• Sudhakar Reddy Baddam · Hyderabad, IN
• Anitha Naredla · Hyderabad, IN
• Kiran Kumar DONIPARTHI · Nellore, IN
• Srividya Ramakrishnan · Hyderabad, IN

Key dates

• Filing date: Apr 13, 2017
• Grant date: Jul 3, 2018
• Expiry date: Apr 13, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present application relates to crystalline and amorphous Vilazodone hydrochloride. The present application further relates to amorphous solid dispersions of vilazodone hydrochloride with pharmaceutically acceptable carriers. The present application also relates to a process for the preparation of form I of vilazodone free base.