C-aryl glucoside derivative, preparation methods thereof, and medical applications thereof

US10011627B2 · kind B2 · utility

Assignee

• Youngene Therapeutics Co., Ltd. · CN

Inventors

• Huijuan Zhong · 安丰镇, CN
• Jianchun Liao · 安丰镇, CN
• Hongping Yu · Shanghai, CN
• Yaochang XU · Shanghai, CN
• Qing Li · Providence, US
• Jianghua Chen · Lo Wu, CN
• Peng Gao · Nanhu, CN
• Songliang Tan · 安丰镇, CN
• Shaobao Wang · 安丰镇, CN

Key dates

• Filing date: Aug 19, 2014
• Grant date: Jul 3, 2018
• Expiry date: Feb 4, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H9/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

C-aryl glucoside derivatives, preparation methods thereof, and medical applications thereof are described. Specifically, compounds represented by formula I, and, tautomers, enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts of the compounds, preparation methods thereof, pharmaceutical compositions containing the compounds, and applications thereof are described. Compounds of formula (I) are useful as therapeutic agents, and particularly as sodium-dependent glucose contransporter protein (SGLT) inhibitors.