PSMA imaging agents

US10011632B2 · kind B2 · utility

Assignee

• Siemens Medical Solutions USA, Inc. · US

Inventors

• Eric Wang · Yonkers, US
• Hartmuth C. Kolb · El Segundo, US
• Anna Katrin Szardenings · San Diego, US
• Changhui Liu · Los Angeles, US
• Joseph C. Walsh · Santa Monica, US
• Gang Chen · Sammamish, US
• Anjana Sinha · San Diego, US
• Dhanalakshmi Kasi · Los Angeles, US
• Chul Yu · Los Angeles, US
• Umesh B. Gangadharmath · Los Angeles, US
• Wei Zhang · San Diego, US
• Tieming Zhao · Los Angeles, US
• Vani P. Mocharla · Los Angeles, US

Key dates

• Filing date: Aug 21, 2012
• Grant date: Jul 3, 2018
• Expiry date: Jan 8, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds for targeting and agents for imaging, Prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.