Alphaviral vectors and cell lines for producing recombinant proteins
US10011847B2 · kind B2 · utility
1Cited by
19References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 20, 2014 |
| Grant date | Jul 3, 2018 |
| Priority date | — |
| Expiry date | May 20, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to polynucleotides and alphaviral vectors for the expression of genes of interest in mammalian cells. Additionally, the invention relates to cells which comprise said polynucleotides and alphaviral vectors and are capable of stably expressing one or more genes of interest. The invention also relates to methods for obtaining said cells, to methods for expressing a gene of interest in said cells, and to methods for replacing the gene of interest stably expressed by said cells with another gene of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.