System and method for delivery of substance into mammalian cells
US10011848B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2016 |
| Grant date | Jul 3, 2018 |
| Priority date | — |
| Expiry date | Nov 9, 2036 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is concerned with a system of delivering particles of nano-scale into mammalian cells with a diameter of 50 μm or less. The system has a container containing the mammalian cells, the particles, a pressure-exerting member for generating transient apertures of substantially 1-200 nm on surface of the cells, a magnetic mechanism configured to generate a magnetic force to act on the pressure-exerting member thus to move the pressure exerting member, a control mechanism for effecting movement of the pressure-exerting member in a predetermined motion pattern, a measuring mechanism configured to indicate magnitude of pressure exerted on surface of the mammalian cells, and a monitoring mechanism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.