Compositions and methods for identifying nucleic acid molecules

US10011870B2 · kind B2 · utility

Assignee

• Natera, Inc. · US

Inventors

• Bernhard Zimmermann · Manteca, US
• Ryan SWENERTON · Millbrae, US
• Matthew Rabinowitz · San Francisco, US
• Styrmir Sigurjonsson · San Jose, US
• George Gemelos · Walnut, US
• Apratim Ganguly · Daly City, US
• Himanshu Sethi · Sunnyvale, US

Key dates

• Filing date: Dec 7, 2016
• Grant date: Jul 3, 2018
• Expiry date: Dec 7, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2563/179
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.