Patent · US Active

Depletion of mouse cells for isolation of human cells

US10012647B2 · kind B2 · utility

0Cited by

0References

6Claims

0Family size

Assignee

Miltenyi Biotec, Inc. · DE

Inventors

Andreas Bosio · Cologne, DE
Olaf Hardt · Cologne, DE
David Joel AGORKU · Cologne, DE

Key dates

Filing date	Jul 15, 2015
Grant date	Jul 3, 2018
Priority date	—
Expiry date	Apr 12, 2036

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/70596
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A process for depleting host cells from a xenograft of human cells on a murine host is disclosed. The process includes fragmenting the xenograft, subjecting the sample to antibodies specific for a murine CD9 epitope coupled to a detection means, depleting the cell suspension from cells bound by the CD9-antibodies using the detection means, and collecting the cells not bound by the CD9-antibodies as target cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.