Patent · US Active

Slow-release conjugates of SN-38

US10016411B2 · kind B2 · utility

2Cited by

1References

4Claims

0Family size

Assignee

PROLYNX LLC · US

Inventors

Gary Ashley · Alameda, US
Eric L. Schneider · Oakland, US

Key dates

Filing date	Oct 3, 2014
Grant date	Jul 10, 2018
Priority date	—
Expiry date	Oct 3, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G83/002
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Conjugates of SN-38 that provide optimal drug release rates and minimize the formation of the corresponding glucuronate are described. The conjugates release SN-38 from a polyethylene glycol through a β-elimination mechanism.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.