Patent · US Active

D-amino acid derivative-modified peptidoglycan and methods of use thereof

US10016498B2 · kind B2 · utility

1Cited by

1References

14Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Carolyn R. Bertozzi · Berkeley, US
Mary Sloan Siegrist Palmore · Berkeley, US
John C. Jewett · Tucson, US
Chelsea G. Gordon · Berkeley, US
Peyton Shieh · Cambridge, US

Key dates

Filing date	Sep 14, 2017
Grant date	Jul 10, 2018
Priority date	—
Expiry date	Sep 14, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/195
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.