Plasma modified medical devices and methods
US10016533B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Mar 13, 2017 |
| Grant date | Jul 10, 2018 |
| Priority date | — |
| Expiry date | Mar 13, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31678
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue, wherein long-lasting and durable bioactive agents or functional groups are deposited on the contacting surface through a unique two-step plasma coating process with deposition of a thin layer of plasma coating using a silicon-containing monomer in the first step and plasma surface modification using a mixture of nitrogen-containing molecules and oxygen-containing molecules in the second step. The two-step plasma coating process enables the implantable medical device to prevent both restenosis and thrombosis under clinical conditions. The invention also relates to surface treatment of metallic and polymeric biomaterials used for making of medical devices with significantly improved clinical performance and durability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.