Patent · US Active

Substituted pyrrolidines as G-protein coupled receptor 43 agonists

US10017468B2 · kind B2 · utility

0Cited by

5References

3Claims

0Family size

Assignee

Ogeda SA · BE

Inventors

Hamid R. Hoveyda · Brussels, BE
Didier Schils · Loupoigne, BE
Ludivine Zoute · Vedrin, BE
Julien Parcq · Lille, FR

Key dates

Filing date	Jun 15, 2017
Grant date	Jul 10, 2018
Priority date	—
Expiry date	Jun 15, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to a process for the preparation of aryl-pyrrolidine carboxylic acid derivative compounds which are useful in treating metabolic diseases, said process consisting of coupling an aryl-pyrrolidine compound with an aryl carboxylic acid compound followed by alkaline or acidic treatment, hydrogenolysis or treatment with a fluoride of the ester intermediate to afford novel aryl-pyrrolidine carboxylic acid derivative compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.