Hydrate of 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride, preparation method and use of the same
US10017472B2 · kind B2 · utility
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Key dates
| Filing date | Mar 2, 2016 |
| Grant date | Jul 10, 2018 |
| Priority date | — |
| Expiry date | Mar 2, 2036 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2009/0095
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride monohydrate and a preparation method of the same. The 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride monohydrate has a very good crystal form and is well suitable for recrystallization purification; further, the effect of impurity removal effect is very good, and any single impurity can be controlled less than 0.1%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.