Patent · US Active

Compounds, compositions, and methods for increasing CFTR activity

US10017503B2 · kind B2 · utility

10Cited by

11References

28Claims

0Family size

Assignee

Proteostasis Therapeutics, Inc. · US

Inventors

Cecilia M. Bastos · Grafton, US
Benito Munoz · San Diego, US
Bradley Tait · Killingworth, US

Key dates

Filing date	Jul 19, 2017
Grant date	Jul 10, 2018
Priority date	—
Expiry date	Jul 19, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The disclosure encompasses compounds having e.g., Formula (Ia) or (Ib), compositions thereof, and methods of modulating CFTR activity. The disclosure also encompasses methods of treating a condition associated with CFTR activity or condition associated with a dysfunction of proteostasis comprising administering to a subject an effective amount of a compound of Formula (I) or (Ib).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.