NAMPT inhibitors and methods

US10017523B2 · kind B2 · utility

Assignee

• Genzyme Corporation · US

Inventors

• Paul Mason · Natick, US
• Kara Carter · Bound Brook Junction, US
• Alexandra Joseph · Lexington, US
• Yiding Hu · Lexington, US
• Jill Gregory · Phoenixville, US
• Zhong Zhao · Munich, DE
• Christopher Yee · Needham, US
• Mohamud Mohamud · Minnetonka, US
• Yibin Xiang · Dracut, US
• Sanjay Danthi · Brookline, US
• Yinyin Huang · Sharon, US
• Andrew Papoulis · Canton, US

Key dates

• Filing date: May 22, 2015
• Grant date: Jul 10, 2018
• Expiry date: May 22, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/60
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention features compounds of Formula (I), Formula (I)-A and Formula (I)-B as disclosed herein, as well as methods of synthesis, therapy, diagnostics, and assays.