MDCK-derived cell strain suspension-cultured in protein-free medium and method for proliferating virus using cell strain
US10017743B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jun 3, 2014 |
| Grant date | Jul 10, 2018 |
| Priority date | — |
| Expiry date | Jun 3, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel MDCK-derived cell line capable of being suspension-cultured in a protein-free medium and a method for proliferating a virus using the MDCK-derived cell line to produce a vaccine. The novel MDCK-derived cell line exhibits high and uniform productivity for various viruses, while causing less viral antigenic variations with low tumorigenicity, and thus can be useful in producing viruses used for vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.