Partially encapsulated waveguide based sensing chips, systems and methods of use

US10018566B2 · kind B2 · utility

Assignee

• LDIP, LLC · US

Inventors

• Ming Tan · Malden, US
• Yun-Pei CHANG · Arcadia, US
• Leyla Sabet · Los Angeles, US
• Ashutosh Shastry · Santa Clara, US
• Christopher Todd · San Jose, US
• Reuven Duer · Ashdod, IL

Key dates

• Filing date: Jul 29, 2015
• Grant date: Jul 10, 2018
• Expiry date: Jan 9, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/648
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Optical readers and alignment tools for detecting the level of an analyte. Described herein are small, disposable partially-encapsulated sensing chips for detecting an analyte level from a fluid sample (e.g., a blood sample) having an edge of the integrated sensing chip exposed to directly expose a plurality of excitation and a collection waveguides, as well as optical readers and methods of operating them. A fluid sample maybe applied to a sensing surface of the sensing chip in the housing so that an analyte level can be optically detected. Also described are methods of sensing an analyte using these devices and systems including an optical detector.