Inhalable pharmaceutical compositions
US10022303B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2013 |
| Grant date | Jul 17, 2018 |
| Priority date | — |
| Expiry date | Feb 28, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/46
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for making inhalable composite particles comprising a pharmaceutically-active agent, the method comprising: a) providing composite particles comprising a millable grinding matrix and a solid pharmaceutically-active agent, wherein the pharmaceutically-active agent has an median particle size on a volume average basis between 50 nm and 3 μm; and b) milling the composite particles in a mill without milling bodies for a time period sufficient to produce inhalable composite particles having a mass median aerodynamic diameter between 1 μm and 20 μm are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.