Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US10022343B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Aug 31, 2017 |
| Grant date | Jul 17, 2018 |
| Priority date | — |
| Expiry date | Aug 31, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C321/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.