Patent · US Active

Encapsulated agents and methods of making and using thereof

US10022451B2 · kind B2 · utility

0Cited by

0References

31Claims

0Family size

Assignee

University of Georgia Research Foundation, Inc. · US

Inventors

Jin Xie · Bositenghu, CN
Zipeng ZHEN · Athens, US
Wei Tang · Shanghai, CN

Key dates

Filing date	May 11, 2015
Grant date	Jul 17, 2018
Priority date	—
Expiry date	Jan 29, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61N2005/0662
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The subject matter disclosed herein relates to compositions that contain a protein cage and a therapeutic agent, such as a photosensitizer. The protein cage is a protein that binds metal ion. The composition can further contain a cell recognition moiety. The methods disclosed are for permeabilizing the endothelial lining of a cancerous tissue or for treating a cancerous tissue to cause therapeutic injury resulting in the reduction of at least one of the surface area, the depth, and the amount of the tissue affected by the cancerous condition, in a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.