Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK
US10023534B2 · kind B2 · utility
0Cited by
7References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 23, 2015 |
| Grant date | Jul 17, 2018 |
| Priority date | — |
| Expiry date | Oct 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds of Formula (I): or a salt thereof, wherein Q is: or; and X, R1a, R1b, R3, R4, and R5 are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.