Patent · US Active

Method for the preparation of 1-(2-halogen-ethyl)-4 piperidine-carboxylic acid ethyl esters

US10023535B2 · kind B2 · utility

0Cited by

1References

16Claims

0Family size

Assignee

OLON S.P.A. · IT

Inventors

Giorgio Bertolini · Sesto San Giovanni, IT
Corrado Colli · Pioltello, IT
Aldo Bianchi · Cesate, IT
Federica Colombo · Milano, IT
Stefano Maiorana · Milano, IT
Filippo NISIC · Pioltello, IT

Key dates

Filing date	Oct 22, 2015
Grant date	Jul 17, 2018
Priority date	—
Expiry date	Oct 22, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F13/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention refers to a process for the preparation of 1-(2-halogen-ethyl)-4-piperidinecarboxylic acid ethyl esters, in particular of 1-(2-chloroethyl)-4 piperidinecarboxylic acid ethyl ester, a versatile synthesis intermediate, particularly useful as an intermediate compound in the synthesis of umeclidinium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.