Patent · US Active

Hydrolysis resistant sialic acid derivatives and methods for their use

US10023601B2 · kind B2 · utility

0Cited by

1References

6Claims

0Family size

Assignee

University of British Columbia · CA

Inventors

Stephen Withers · Vancouver, CA
Thomas J. Morley · New Haven, US
Lars Baumann · Vancouver, CA

Key dates

Filing date	Feb 18, 2015
Grant date	Jul 17, 2018
Priority date	—
Expiry date	Feb 26, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P21/005
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, improved biological stability or an improved pharmacokinetic property.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.