Protein purification methods to remove impurities
US10023608B1 · kind B1 · utility
8Cited by
37References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2014 |
| Grant date | Jul 17, 2018 |
| Priority date | — |
| Expiry date | Nov 15, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods of purifying a protein sample. More specifically, provide are methods of removing or reducing the amount of high molecular weight species and/or high mannose species from a protein sample using a mixed mode chromatography step and a hydrophobic interaction chromatography step.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.