Patent · US Active

Cell line expressing single chain factor VIII polypeptides and uses thereof

US10023628B2 · kind B2 · utility

0Cited by

50References

17Claims

0Family size

Assignee

BIOVERATIV THERAPEUTICS INC. · US

Inventors

Susan Low · Pepperell, US
Jennifer A. Dumont · Groton, US
Alan J. Bitonti · Acton, US

Key dates

Filing date	Jul 5, 2013
Grant date	Jul 17, 2018
Priority date	—
Expiry date	Jul 5, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/31
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides cell lines for producing single chain FVIII polypeptides, e.g., chimeric single chain FVIII polypeptides, methods of producing single chain FVIII polypeptides, single chain FVIII polypeptides, and methods of treating Hemophilia A with a single chain Factor VIII polypeptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.