Patent · US Active

Processes for the production of chemically-modified heparins

US10023659B2 · kind B2 · utility

0Cited by
3References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 19, 2014
Grant dateJul 17, 2018
Priority date
Expiry dateSep 10, 2034

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P15/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for the production of heparin derivatives having an average molecular weight of from about 4.6 to about 6.9 kDa and an anti-factor Xa activity of less than about 10 IU/mg, comprising the steps of oxidation of unfractionated heparin, depolymerisation and reduction of resulting terminal groups.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.