Method and system for extraction and normalization of relationships via ontology induction
US10025774B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 26, 2012 |
| Grant date | Jul 17, 2018 |
| Priority date | — |
| Expiry date | May 26, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B50/10
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods for developing an ontology of pharmacogenomics (PGx) relationships starting from a lexicon of key pharmacogenomic entities and a syntactic parse is described. The syntactic structure of PGx statements is used to systematically extract commonly occurring relationships and to map them to a common schema. In an embodiment, extracted relationships have a 70-87.7% precision and involve not only key PGx entities such as genes, drugs, and phenotypes (e.g., VKORC1, warfarin, clotting disorder), but also critical entities that are frequently modified by these key entities (e.g., VKORC1 polymorphism, warfarin response, clotting disorder treatment).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.