Non-invasive systems and methods to detect cortical spreading depression for the detection and assessment of brain injury and concussion
US10028694B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 23, 2015 |
| Grant date | Jul 24, 2018 |
| Priority date | — |
| Expiry date | Apr 11, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2562/046
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides systems and methods for detection and diagnosis of concussion and/or acute neurologic injury comprising a portable headwear-based electrode array and computerized control system to automatically and accurately detect cortical spreading depression and acute neurological injury-based peri-infarct depolarization (CSD/PID). The portable headwear-based electrode system is applied to a patient or athlete, and is capable of performing an assessment automatically and with minimal user input. The user display indicates the presence of CSD/PID, gauges its severity and location, and stores the information for future use by medical professionals. The systems and methods of the invention use an instrumented DC-coupled electrode/amplifier array which performs real-time data analysis using unique algorithms to produce a voltage intensity-map revealing the temporally propagating wave depressed voltage across the scalp that originates from a CSD/PID on the brain surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.