Drug-eluting articles with improved drug release profiles
US10029034B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 15, 2005 |
| Grant date | Jul 24, 2018 |
| Priority date | — |
| Expiry date | Feb 2, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/61
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to drug-eluting articles with multiple polymeric coatings arranged and constructed to provide improved drug release profiles. Specifically, the present invention relates to drug-eluting articles that each comprises a substrate, a first polymeric layer over said substrate, and a second polymeric layer over said first polymeric layer. The first polymeric layer comprises at least a first biocompatible polymer and at least a first pharmacologically active compound that is encapsulated in the first biocompatible polymer. The second polymeric layer comprises at least a second biocompatible polymer having a degradability that is higher than that of the first biocompatible polymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.