Single-use bioreactor and head plate, and a process for manufacturing same

US10030220B2 · kind B2 · utility

Assignee

• Eppendorf AG · DE

Inventors

• Matthias Arnold · Zolling, DE
• Heinz-Gerhard Kohn · Dransfeld, DE
• Nico Gülzow · Hamburg, DE
• Sven Eikelmann · Petershagen, DE
• Sebastian Selzer · Aachen, DE
• Jochen Beese · Norderstedt, DE
• Christopher A. Gunther · Bellevue, US
• Eckart Kopowski · Braunschweig, DE

Key dates

• Filing date: Jun 13, 2013
• Grant date: Jul 24, 2018
• Expiry date: Aug 10, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A single-use bioreactor, suitable in particular for use in a parallel bioreactor system for applications in cell culture and/or microbiology, a head plate for such a single-use bioreactor and a process for manufacturing the single-use bioreactor and the head plate. The single-use bioreactor comprises a head plate, a dimensionally stable container and a mixer, the head plate and the container enclosing a reaction chamber, and the mixer having a mixer shaft and a stirring member, said mixer shaft being mounted rotatably about a rotational axis in a bearing and the stirring member being fastened torsionally rigidly to the mixer shaft. The mixer and the bearing are arranged entirely within the reaction chamber and the mixer shaft has a magnetic portion which is arranged and adapted in such a way that it can be coupled magnetically in an axial direction to a rotary drive.