Quantification of the relative amount of water in the tissue microcapillary network
US10031204B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 24, 2013 |
| Grant date | Jul 24, 2018 |
| Priority date | — |
| Expiry date | Aug 22, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/5608
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention discloses a method for magnetic resonance (MR) imaging comprising: acquiring at least two MR images with different motion-weighting originating from a RF and gradient pulse sequence causing signal attenuation from diffusion but not flow (flow-compensated data); acquiring at least two MR images with different motion-weighting originating from a RF and gradient pulse sequence causing signal attenuation from diffusion and flow (non-compensated data); performing a model fit to the flow-compensated and non-compensated data in which at least one of the adjustable parameters are constrained to be the same for both sets of data; and obtaining quantitative information on microscopic flow by extracting at least one parameter of the intravoxel incoherent motion (IVIM) effect from the model fit, said method being directed to diffusion-perfusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.