Small heat shock proteins and active fragments thereof as a therapy for inflammation and ischemia

US10034915B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Lawrence Steinman · Stanford, US
• Jonathan B. Rothbard · Woodside, US

Key dates

• Filing date: Jun 22, 2012
• Grant date: Jul 31, 2018
• Expiry date: Jun 22, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides methods for treating inflammatory diseases by administering to the subject an effective amount of specific peptides derived from HSPB5, where the dose is effective to suppress or prevent initiation, progression, or relapses of disease, including the progression of established disease.