Heterocyclic kinase inhibitors

US10035777B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Carolyn Diane Dzierba · Middletown, US
• Joanne J. Bronson · Madison, US
• John E. Macor · Guilford, US
• Bireshwar Dasgupta · Middletown, US
• Susheel Jethanand Nara · Mumbai, IN
• Vivekananda M. Vrudhula · Killingworth, US
• Senliang Pan · Woodbridge, US
• Richard A. Hartz · Kennett Square, US
• Ramkumar Rajamani · Wallingford, US

Key dates

• Filing date: Jul 27, 2015
• Grant date: Jul 31, 2018
• Expiry date: Jul 27, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.