Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation
US10036012B2 · kind B2 · utility
6Cited by
208References
22Claims
0Family size
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Key dates
| Filing date | Mar 28, 2017 |
| Grant date | Jul 31, 2018 |
| Priority date | — |
| Expiry date | Mar 28, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2565/519
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods, compositions and kits for targeted nucleic acid sequence enrichment in a nucleic acid sample and for high efficiency nucleic acid library generation for next generation sequencing (NGS). Specifically, the methods, compositions and kits provided herein are useful for the production and capture of amplification-ready, target-specific and strand-specific regions of interest from nucleic acid samples containing complex DNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.