Generation of discovery ion currents and mass spectrometry and uses thereof
US10037872B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 29, 2017 |
| Grant date | Jul 31, 2018 |
| Priority date | — |
| Expiry date | Aug 29, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/82
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Systems for the generation of discovery ion currents. One of the systems includes a mass spectrometer providing ion current measurement. The system includes a controller coupled to the mass spectrometer. The system also includes a liquid handler coupled to the controller and the mass spectrometer. The controller is configured to identify a base average ion current of each mass to charge interval, the mass to charge interval comprising at least one mass to charge channel. The controller is configured to calculate a relative change between a current ion current measurement for a charge interval to the base average for the charge interval. The controller is configured to compare the relative change to a threshold. The controller is also configured to, in response to determining that the relative change exceeds the threshold, start fraction collection using the liquid handler.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.