Automatic determination of demultiplexing matrix for ion mobility spectrometry and mass spectrometry
US10037873B2 · kind B2 · utility
18Cited by
2References
20Claims
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Key dates
| Filing date | Oct 2, 2015 |
| Grant date | Jul 31, 2018 |
| Priority date | — |
| Expiry date | Sep 28, 2036 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/40
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
Multiplexed ion mobility spectrometry (IMS), mass spectrometry (MS) such as time-of-flight mass spectrometry (TOFMS), or hybrid IM-MS is carried out on a sample, and the resulting measurement data are deconvoluted. A pulse sequence controlling ion pulsing is utilized in conjunction with the multiplexing. The pulse sequence may be modified based on the raw measurement data acquired. A demultiplexing matrix based on the modified pulse sequence is utilized to improve deconvolution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.