Patent · US Active

Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies

US10039735B2 · kind B2 · utility

17Cited by

29References

22Claims

0Family size

Assignee

UCL BUSINESS PLC · GB

Inventors

Rajiv Jalan · London, GB
Rajeshwar Prosad Mookerjee · London, GB
Krista Rombouts · London, GB
Fausto Andreola · London, GB
Francesco De Chiara · London, GB
Karen Louise Thomsen · London, GB

Key dates

Filing date	Nov 23, 2015
Grant date	Aug 7, 2018
Priority date	—
Expiry date	Nov 23, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are methods of preventing, treating, and delaying the onset or progression of diseases associated with hepatic stellate cells (HSCs), such as non-alcoholic fatty liver disease (NAFLD), fibrosis, and liver cancer, using ammonia-lowering therapies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.