Compounds, systems, and methods for monitoring and treating a surface of a subject
US10039842B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 23, 2017 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Aug 23, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2013/0097
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, systems, and methods are provided for the design and assembly of a non-invasive, analyte sensing dressing. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The device emits a detectable signal when the sensor is excited in the presence of the analyte. In one version of the dressing, the sensor includes a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The metallated porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity can be used as an indicator for oxygen concentration. The porphyrin can have the Formula (II): wherein R1 includes a moiety selected from the group consisting of alkynl groups, triazolyl groups, alkylglutamate groups, and a pair of alkylglutamate groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.