Patent · US Active

Apparatus and methods for integrated sample preparation, reaction and detection

US10040071B2 · kind B2 · utility

3Cited by
163References
9Claims
0Family size

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Key dates

Filing dateDec 1, 2016
Grant dateAug 7, 2018
Priority date
Expiry dateDec 1, 2036

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/255
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided, as are methods for using such cartridges. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.

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