Patent · US Active

Intermediates for macrocyclic compounds

US10040751B2 · kind B2 · utility

0Cited by
101References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 1, 2015
Grant dateAug 7, 2018
Priority date
Expiry dateOct 1, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/0827
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as described in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.