Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
US10040752B2 · kind B2 · utility
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6References
22Claims
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Key dates
| Filing date | Aug 24, 2016 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Aug 24, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.